Journal: Diagnostics

Article Title: Continuous Glucose Monitoring Systems: A Review

doi: 10.3390/diagnostics3040385

Figure Lengend Snippet: Continuous glucose monitoring systems. MARD, mean absolute relative difference; EGA, error grid analysis; CE, Conformité Européenne; DG4P, Dexcom G4 TM PLATINUM; FN, FreeStyle Navigator ® .

Article Snippet: Dexcom G4 TM PLATINUM (Dexcom) , Target site: skin Technology used: glucose sensor; sensor lifespan: 168 h; length of sensor probe: 13 mm; gauge of sensor probe: 26 mm; sensor warm up: 2 h; calibration every 12 h, but twice within the first 30 min. Advantages: compact, wearable and light-weight; measures glucose continuously every 5 min; transmit glucose readings to the receiver up to a distance of 6 m; employs a very thin glucose sensor that can be used for up to seven days and has the same diameter as a human hair; high precision; receiver with colored screen and alarm alerts for high and low glucose levels and when the glucose levels are rising or falling quickly; comes with Dexcom STUDIO TM data management software, which enables simple navigation and an illustrative visual for the quick and easy identification of glucose patterns. Disadvantages: invasive; requires calibration with blood glucose testing every 12 h; requires a change of the sensor after a few days. Reliability: aggregate MARD = 13%; 90% of DG4P sensors had an individual MARD of ≤20%; DG4P had a mean absolute difference of 11 mg/dL for hypoglycemia (YSI < 70 mg/dL) [ ]. Cost: US $1,198 for CGMS and US $349 for a four-pack of sensors. Daily cost of US $6.70. Availability: USA, European Union, Asian and Latin American countries that recognize the CE mark. .

Techniques: Software, Raman Spectroscopy, Transmission Assay, Spectroscopy